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If it can cause a blistering rash on the skin, how do I treat it?
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Guess anything is possible. We picked it when I was a child using our bare hands. You know the rule of boiling to eat.? Never read a word to truth, but we always put the leaves in water boiled it, poured the water off, doing this 4-5 times. Were told it was poison to eat if not done correctly. So we always did. Never testing to truth.

Have had bathtub full to wash and used bare hands without any break outs. Did you mean eating it or touching it to break outs? Hope this helps, is all I know about it.
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I am a horrible mess. Did you figure out how to treat it? Pokeweed is officially my worst enemy.
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